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. 2021 Jan 21;106(4):947–957. doi: 10.3324/haematol.2020.262485

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Copyright© 2021 Ferrata Storti Foundation

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Figure 3. — Overview of soluble factors used in the production of platelets and erythrocytes in vitro. Different cocktails of cytokines, pharmacological agents and/or co-culture with feeder cells have been used to generate platelets and erythrocytes in vitro. HSC: hematopoietic stem cell; FLT3: Fms related tyrosine kinase 3; SCF: stem cell factor; IL: interleukin; IGF-1: insulin-like growth factor-1; TPO: thrombopoietin; EPO: erythropoietin; SR1: stemRegenin 1; AhR: aryl hydrocarbon receptor. The figure was created using Servier Medical Art templates licensed under a Creative Commons Attribution 3.0 Unported License (https://smart.servier.com).