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. 2021 Apr 2;92:104823. doi: 10.1016/j.meegid.2021.104823

Table 1.

Conserved Regions (CnRs) as derived from 10,664 SARS-CoV-2 genomes with associated details.

DNA sequence of Protein Length BLAST Specificity % of BLAST Specificity Coding Starting Ending Length Coded
Conserved Region (CnR) Sequence of CnR Score of CnR Score as Query Coverage Region (CR) Coordinate Coordinate of Protein Proteins
7622-GTTAATTGTGATACATTCTGTGCTGGTAGTACATTTATTAGTGATGAAGTTGCGAGAGAC-7681 VNCDTFCAGSTFISDEVARD 60 111 100 ORF1ab 266 21,552 21,287 NSP3
8918-TTACCTAGAGTTTTTAGTGCAGTTGGTAACATCTGTTACACACCATCAAAACTTATAGAGTACACTG-8984 LPRVFSAVGNICYTPSKLIEYT 67 124 100 ORF1ab 266 21,552 21,287 NSP4
11277-ATACTAGTTTGTCTGGTTTTAAGCTAAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACA-11395 TSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWT 119 220 100 ORF1ab 266 21,552 21,287 NSP6
12,438-CCTTGAACATAATACCTCTTACAACAGCAGCCAAACTAATGGTTGTCATACCAGACTATAAC-12499 LNIIPLTTAAKLMVVIPDYN 62 115 100 ORF1ab 266 21,552 21,287 NSP8
13,924-TGGTATGATTTTGTAGAAAACCCAGATATATTACGCGTATACGCCAACTTAGGTGAACGTGTACGCCAAGCTTTGTT-14000 WYDFVENPDILRVYANLGERVRQAL 77 143 100 ORF1ab 266 21,552 21,287 RdRp
15,607-TTACAACACAGACTTTATGAGTGTCTCTATAGAAATAGAGATGTTGACACAGACTTTGTGAATGAGTTTTACGCAT-15682 LQHRLYECLYRNRDVDTDFVNEFYA 76 141 100 ORF1ab 266 21,552 21,287 RdRp
16,730-TTTCATGGGAAGTTGGTAAACCTAGACCACCACTTAACCGAAATTATGTCTTTACTGGTTATCGTGTAACTAAAAACAGTAAAGTACAAAT-16820 SWEVGKPRPPLNRNYVFTGYRVTKNSKVQ 91 169 100 ORF1ab 266 21,552 21,287 Helicase
17,215-ATAGATAAATGTAGTAGAATTATACCTGCACGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTGAATTCAACATTAGAACAGTATGT-17303 IDKCSRIIPARARVECFDKFKVNSTLEQY 89 165 100 ORF1ab 266 21,552 21,287 Helicase
17,612-ATAAGCTTAAAGCACATAAAGACAAATCAGCTCAATGCTTTAAAATGTTTTATAAGGGTG-17671 KLKAHKDKSAQCFKMFYKG 60 111 100 ORF1ab 266 21,552 21,287 Helicase
19,851-GGACATTGCTGCTAATACTGTGATCTGGGACTACAAAAGAGATGCTCCAGCACATATATCTACTATTGGTGTTTGTTCTATGACT-19935 DIAANTVIWDYKRDAPAHISTIGVCSMT 85 158 100 ORF1ab 266 21,552 21,287 endoRNAse
20,757-TGCAACATTACCTAAAGGCATAATGATGAATGTCGCAAAATATACTCAACTGTGTCAATATTTAAACAC-20825 ATLPKGIMMNVAKYTQLCQYLN 69 128 100 ORF1ab 266 21,552 21,287 2′- O- RMT
23,732-ACAGAAATTCTACCAGTGTCTATGACCAAGACATCAGTAGATTGTACAATGTACATTTGTGGTGATT-23798 TEILPVSMTKTSVDCTMYICGD 67 124 100 Spike 21,563 25,381 3819 Spike glycoprotein
24,406-TCAAGATGTGGTCAACCAAAATGCACAAGCTTTAAACACGCTTGTTAAACAACTTAGCTCCAA-24468 QDVVNQNAQALNTLVKQLSS 63 117 100 Spike 21,563 25,381 3819 Spike glycoprotein
25,990-TGTGTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCAACTCAATTGAGTACAGA-26057 CVVLHSYFTSDYYQLYSTQLST 68 126 100 ORF3a 25,393 26,217 825 ORF3a protein
26,560-TTAAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTCCTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTA-26638 KKLLEQWNLVIGFLFLTWICLLQFA 79 147 100 Membrane 26,523 27,188 666 Membrane glycoprotein
27,129-AACTATAAATTAAACACAGACCATTCCAGTAGCAGTGACAATATTGCTTTGCTTGTACAGT-27189 NYKLNTDHSSSSDNIALLVQ 61 113 100 Membrane 26,523 27,188 666 Membrane glycoprotein
28,518-ACCAAATTGGCTACTACCGAAGAGCTACCAGACGAATTCGTGGTGGTGACGGTAAAATGAAA-28579 QIGYYRRATRRIRGGDGKMK 62 115 100 Nucleocapsid 28,274 29,530 1257 Nucleocapsid protein