Table 3.
Summary of most Immunogenic and Antigenic Epitopes for MHC-I, MHC-II restricted T-cell and B-cell Epitopes for 17 CnRs.
| Coded | MHC-I restricted T-cell | MHC-II restricted T-cell | B-cell |
|---|---|---|---|
| Proteins | Epitopes | Epitopes | Epitopes |
| NSP3 | STFISDEVAR | FCAGSTFISDEVARD | CDTFCAGSTFISDEVA |
| DTFCAGSTF | DTFCAGSTFISDEVA | ||
| NSP4 | YTPSKLIEY | VGNICYTPSKLIEYT | AVGNICYTPSKLIEYT |
| FSAVGNICY | |||
| NSP6 | TVYDDGARR | ASAVVLLILMTARTV | LILMTARTVYDDGARR |
| ILMTARTVY | SGFKLKDCVMYASAVV | ||
| NSP8 | TTAAKLMVV | LNIIPLTTAAKLMVV | LNIIPLTTAAKLMVVI |
| NIIPLTTAAK | |||
| RdRp | VENPDILRVY | ILRVYANLGERVRQA | YDFVENPDILRVYANL |
| RVYANLGER | DILRVYANLGERVRQA | ||
| RdRp | DTDFVNEFY | RNRDVDTDFVNEFYA | HRLYECLYRNRDVDTD |
| YRNRDVDTDFVNEFY | YRNRDVDTDFVNEFYA | ||
| Helicase | YVFTGYRVTK | NYVFTGYRVTKNSKV | SWEVGKPRPPLNRNYV |
| PPLNRNYVFTGYRVTK | |||
| Helicase | KVNSTLEQY | ECFDKFKVNSTLEQY | CSRIIPARARVECFDK |
| IPARARVECF | KCSRIIPARARVECF | ||
| Helicase | KSAQCFKMF | AHKDKSAQCFKMFYK | HKDKSAQCFK |
| KSAQCFKMFY | |||
| endoRNAse | DAPAHISTI | IWDYKRDAPAHISTI | ANTVIWDYKRDAPAHI |
| NTVIWDYKR | WDYKRDAPAHISTIG | ||
| 2’-O-RMT | KYTQLCQYL | PKGIMMNVAKYTQLC | PKGIMMNVAKYTQLCQ |
| Spike glycoprotein | EILPVSMTK | PVSMTKTSVDCTMYI | LPVSMTKTSVDCTMYI |
| TEILPVSMTKTSVDC | |||
| Spike glycoprotein | ALNTLVKQL | QDVVNQNAQALNTLV | NQNAQALNTLVKQLSS |
| NAQALNTLV | DVVNQNAQALNTLVK | ||
| ORF3a protein | FTSDYYQLY | LHSYFTSDYYQLYST | LHSYFTSDYYQLYSTQ |
| YYQLYSTQL | HSYFTSDYYQLYSTQ | ||
| Membrane glycoprotein | KLLEQWNLV | WNLVIGFLFLTWICL | LVIGFLFLTWICLLQF |
| LVIGFLFLTW | |||
| Membrane glycoprotein | SSDNIALLV | NYKLNTDHSSSSDNI | YKLNTDHSSSSDNIAL |
| SSSDNIALL | |||
| Nucleocapsid protein | GYYRRATRR | IGYYRRATRRIRGGD | GYYRRATRRIRGGDGK |
| IGYYRRATR |