Table 4.
List of proposed epitopes for SARS-CoV-2 as given in the literature.
| Source | Coded Proteins | MHC-I restricted T-cell Epitopes | MHC-II restricted T-cell Epitopes | B-cell Epitopes |
|---|---|---|---|---|
| Baruah and Bose (2020) | Spike glycoprotein | YLQPRTFLL | NA | CVNLTTRTQLPPAYTN |
| GVYFASTEK | NVTWFHAIHVSGTNG | |||
| EPVLKGVKL | SFSTFKCYGVSPTKLND | |||
| Bency and Helen (2020) | Spike glycoprotein | KIADYNYKL | VVFLHVTYV | MDLEGKQGNFKNL |
| CYGVSPTKL | IGINITRFQ | YYVGYLQPR | ||
| VVVLSFELL | FNCYFPLQS | NITNLCPFGE | ||
| Bhatnager et al. (2020) | Spike glycoprotein | LTDEMIAQY | VASQSIIAYTMSLGA | KEEQIGKCSTR |
| LLTDEMIAQY | LTDEMIAQYTSALLA | ELGKYEQYGPGPGKWP | ||
| IPFAMQMAY | VLNDILSRLDKVEAE | IRAGPGPGGNC | ||
| Bhattacharya et al. (2020a) | Spike glycoprotein | SQCVNLTTR | IHVSGTNGT | SQCVNLTTRTQLPPAYTNSFTRGVY |
| YTNSFTRGV | VYYHKNNKS | FSNVTWFHAIHVSGTNGTKRFDN | ||
| GVYYHKNNK | LVRDLPQGF | DPFLGVYYHKNNKSWME | ||
| Chen et al. (2020) | Spike glycoprotein | LSPRWYFYY | IKLDDKDPN | EVRQIAPGQTGKIADY |
| RSRNSSRNS | RSGARSKQR | GCLIGAEHVNNSYECD | ||
| IGYYRRATR | RIGMEVTPS | FAMQMAYRFNGIGVTQ | ||
| Crooke et al. (2020) | Membrane glycoprotein | ATSRTLSYY | TLSYYKLGASQRVAG | EVTPSGTWL |
| RLFARTRSM | RTLSYYKLGASQRVA | KLDDKDPNFK | ||
| YANRNRFLY | ASFRLFARTRSMWSF | KTFPPTEPKKDKKKKADETQALPQ | ||
| Grifoni et al. (2020a) | Spike glycoprotein | NLTTRTQL | TQDLFLPFFSNVTWF | DAVDCALDPLSETKCTLKSFTVEKGIYQTSN |
| LPPAYTNSF | SLLIVNNATNVVIKV | VCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVI | ||
| KVFRSSVLH | LPFFSNVTWFHAIHV | GTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGS | ||
| Gupta et al. (2020) | Spike glycoprotein | VRFPNITNL | NVTWFHAIHV | GDEVRQIAPGQTGKIADYNYKLP |
| YQPYRVVVL | ||||
| PYRVVVLSF | ||||
| Kar et al. (2020) | Spike glycoprotein | QIITTDNTF | INITRFQTLLALHRS | FSYTESLAGKREMAII |
| YQPYRVVVL | GINITRFQTLLALHR | HAGPGPGPY | ||
| FTISVTTEI | GWTFGAGAALQIPFA | KMGPGPGTRFA | ||
| Kwarteng et al. (2020) | 1*Nucleocapsid protein | KTFPPTEPK | AQFAPSASAFFGMSR | AGLPYGANK |
| SSPDDQIGY | IAQFAPSASAFFGMS | SKQLQQSMSSADS | ||
| SSPDDQIGYY | PQIAQFAPSASAFFG | RRIRGGDGKMKDL | ||
| Lim et al. (2020) | Spike glycoprotein | YLQPRTFLL | VVLSFELLHAPATVC | SQCVNLTTRTQLPPAYTNSFTRGVY |
| KIADYNYKL | QQLIRAAEIRASANL | DPFLGVYYHKNNKSWME | ||
| SIIAYTMSL | GNYNYLYRLFRKSNL | NLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTN | ||
| Naz et al. (2020a) | Spike glycoprotein | GVYFASTEK | EFVFKNIDGYFKIYS | YNSASFSTFKCYGVSPTKLNDLCFT |
| STQDLFLPF | QPYRVVVLSFELLHA | |||
| KTSVDCTMY | MTKTSVDCTMYICGD | |||
| Ong et al. (2020) | NSP3 | STNVTIATY | ISNSWLMWLIINLVQ | EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATS |
| RMYIFFASF | LAYILFTRFFYVLGL | EEEQEEDWLDDD | ||
| AEWFLAYIL | AAIMQLFFSYFAVHF | VGQQDGSEDNQ | ||
| Poran et al. (2020) | Spike glycoprotein | YQPYRVVVL | TPPIKDFGGFNFSQILPDPSKPSKR | NA |
| FVFLVLLPL | EIDRLNEVAKNLNESLIDLQELGKY | |||
| CVADYSVLY | EKGIYQTSNFRVQPTESIVRFPNIT | |||
| Rakib et al. (2020) | Spike glycoprotein | WTAGAAAYY | LIVNNATNV | RTQLPPAYTNS |
| CNDPFLGVY | IVNNATNVV | SGTNGTKRFDN | ||
| GAAAYYVGY | SKTQSLLIV | LTPGDSSSGWTAG | ||
| Singh et al. (2020) | Nucleocapsid protein | AQFAPSASA | AQFAPSASAFFGMSR | KEDLKFP |
| GDAALALLL | GDAALALLLLDRLNQ | IKLDDKDPNFKDQ | ||
| GMSRIGMEV | ASAFFGMSRIGMEVT | PPTEPKKDKKKKADETQALPQRQKKQQTVT | ||
| Vashi et al. (2020) | Spike glycoprotein | RTQLPPAY | MFVFLVLLPLVSSQC | PPAYTNSFTRGVYY |
| RTQLPPA | MFVFLVLLPLVSSQCVN | HVSGTNGTKRFDN | ||
| LPPAYTNSF | QGNFKNLREFVFKNI | YYHKNNKSWMES | ||
| Yadav et al. (2020) | Spike glycoprotein | GVYFASTEK | NA | HRSYLTPGDSSSGWTA |
| FEYVSQPFL | FPNITNLCPFGEVFNA | |||
| WTAGAAAYY | EVIQIAPGQTGKIADY |