Table 1.

The full list of histological and molecular IA markers in each group. Abbreviation: Gene‐based markers are highlighted with an asterisk. The full names for the abbreviations of the histological and molecular markers are available in the Table S7 in Supporting Information.

Group 1: nIA > IA

AT1, AT2, ACE, CASP8, CAV1, DPD, DPD + PYD/Collagen, DES, FLN‐C, ITGA1, ITGA2, IL‐10, MLCK, MYL9, SMTN, SORBS2, VCL, WWOX *ADH1C, *AHF (*F8), *AOC3, *ANXA2P1, *ANXA2P3, *APOL3, *BCL2, *BST2, *BCYRN1, *CMYA5, *CD97, *CCL15, *CXCL12, *CXCL14, *CFD, *CPNE9, *DPT, *FTH1P3, *FYN, *GJB6, *GREB1, *GBP2, *HSP90AA6P, *HSP90AB3P, *HIST1H3J, *JCHAIN, *IFITM4P, *IFIH1, *MHC1 (*HLA‐B), *MHC1 (*HLA‐C), *MHC1 (*HLA‐E), *MHC1 (*HLA‐F), *HLA‐G, *HLA‐DRB3, *KCNT1, *MASP2, *MATN2, *MARCH8, *MFAP4, *MGLL, *MMRN2, *MBP, *MYL9, *NFATC3, *NF‐κB2, *NR3C1, *OTUB1, *PLN, *PLA2G4C, *PRELP, *PTGDS, *PTGER4, *PSMB8, *PSMB9, *PRKRA, *RETREG1, *RPL13AP20, *SERPIND1, *STAT3, *SLC13A3, *SORBS1, *SWAP70T1, *TAPBIN1, *TNC, *TCF7, *TMEM45B, *TPI1P2, *TNS1, *vWF

Group 2: IA > nIA

AZU1, CD62E, CD4+, CD8+, FADD, Gelatin lysis, HA, MMP‐1, MMP‐2, MMP‐3, MT1‐MMP, MCP1 (CCL2), NGF, PLG, PSF, RAI, S100A4, SMOC1, TM9SF1, tPA (uPA), VCAM1, XO (XAQ) *A2M, *ACTB, *AJ, *ATF5, *AG, *BPI, *BCR, *BLM, *CAM, *CCC, *CCRI, *CC/RGCC, *CHST15, *CLDN5, *CLIP2, *CPZ, *CTSB, *DEFB1, *DVAF‐, *E2F4, *FAK, *FBN2, *FLRT3, *GJ, *H19, *HAAO, *HAMP, *HNF4, *HNF6, *HP, *HRH2, *IKBKG, *INS, *JUN, *LILRB2, *LTEM, *LIFR, *LTD, *LTP, *LYZ, *LOXL1, *LOXL2, *LOXL3, *LOXL4, *MHC2 (*HLA‐A), *MAPK, *MMP13, *MMP16, *MG, *MEX3B, *MCP1 (*CCL2), *MTND6P4, *mTOR, *MUC3B, *MYH11, *NK, *NLRI, *NUFIP2, *NIFK, *PAX5, *PTHLH, *POSTN, *PIK3R5, *PLVAP, *PLEK, *RAC, *SAMSN1, *SFRP2, *SCG2, *SERPINA1, *SNARE, *SOX4, *SMOC1, *TJ, *TLR4, *HTF4, *TGF‐β, *TOG1, *TMEM132B, *TWIST1, *VEGF, *WAS

Group 3: UIA > RIA

Presence of atherosclerosis, Presence of SMC layer, Presence of Collagen, Resistance to biomechanical tests, AHF (F8), AHSG, ASPN (PLAP1), Bad (Phospho‐Bad), BGN, CAT, CHST14, CRAT, CRABP1, CXCL12 (SDF1), DKZp686H1812, DKZp686K06110, DPT (TRAMP), HLA‐A, HLA‐B, HSPG, IL6, mTOR (Phospho‐mTOR), OLFML1, OLFML3, OPN, PINCH, PLC, PTGDS, vWF *BCL2L1, *BCL2, *CAMK2A, *CD69, *CDKN2A, *cDNA FLJ51023, *cDNA FLJ58762 *COL, *DDN, *DOK6, *ENG, *FAM110C, *HES1, *HLA‐DPB1, *IGHG4, *KRT17, *KLF2, *KLF12, *KLF15, *MYOZ3, *PACSIN1, *RXFP1, *TIMP2, *TIMP1, *TIMP3, *TIMP4,*TPH1, *TIE1, *VCAM1

Group 4: RIA > UIA

Apoptosis, Endothelial layer damage, Intraluminal Thrombosis, AA1 (CC1), ALOX12, ASC, CASP1, C1q, C3b, C3c, C3d, C4b, C5b, CASP9, CC1, CD45+, CD68+, CD163+, CD3, CD45RO (CD45RB), CTSD, CTSG, COX‐2, DEFA3, ECP, ECRP, ELA2, EPO, FN, GP1BB, GPA, HLA‐DR, HMGB1, HO1, ICAM1, IgM, IgG, IgA, IL‐1β, ITGAM (CD11b), ITGA2B, ITGB3, JNK (MAPK), KLF5, Ki67, Laminin, LF, LTF, MAC, MDA, MMP9, MPO, NCF1C, NCF4, NF‐κB, NLRP3, PMP2, PNUT, PGE2, PYCARD, RAC2, RETN, S100P, SERPINF2, TC1, TGF‐α, TLR, VEGF *ADAMTS1, *ALDOB, *AGT, *ATP1B2, *BAX, *BID, *CD163, *CD300C, *CD300E, *cDNA FLJ57667, *CLEC5A, *CTSD, *DAXX, *ETS, *FAS, *HPSE, *HIF1A, *KCNA5, *MARCO, *MMP2, *MMP14, *MT1X, *MT1E, *MT1G, *MT1M, *MT1A, *MT2A, *MT1B, *MPO, *NQO1, *NOS1, *NOS1AP, *OSCAR, *OLR1, *PDCD5, *RYR2, *S100A8, *S100A9, *S100A12, *SEMA3A, *TFAP2A, *TGFBI, *TNF‐α (*TNFRSF1A, *TNFRSF1B)