Table 5.
Meningeal B cells and axon loss in F+ SPMS.
| A CST | L CST | D Col | All tracts | ||
|---|---|---|---|---|---|
| F+ SPMS | CD20 | r = 0.714 P = 0.136 | r = 0.893 P = 0.012 | r = 0.886 P = 0.033 | r = 0.684 P < 0.001 |
| CD8 | r = 0.172 P = 0.782 | r = 0.801 P = 0.098 | r = −0.420 P = 0.482 | r = 0.035 P = 0.903 | |
| CD4 | r = −0.208 P = 0.737 | r = 0.439 P = 0.193 | r = −0.542 P = 0.346 | r = −0.189 P = 0.499 | |
| Total | r = 0.119 P = 0.848 | r = 0.762 P = 0.134 | r = −0.357 P = 0.555 | r = 0.120 P = 0.680 | |
| F− SPMS | CD20 | r = −0.029 P > 0.999 | r = −0.028 P = 0.989 | r = 0.046 P = 0.931 | r = −0.066 P = 0.795 |
| CD8 | r = −0.429 P = 0.419 | r = −0.371 P = 0.497 | r = −0.370 P = 0.470 | r = −0.179 P = 0.478 | |
| CD4 | r = −0.543 P = 0.297 | r = −0.314 P = 0.564 | r = −0.553 P = 0.255 | r = −0.379 P = 0.121 | |
| Total | r = −0.314 P = 0.564 | r = −0.486 P = 0.356 | r = −0.423 P = 0.398 | r = −0.166 P = 0.510 |
Correlating B cells, T cell and total B and T cells with axon loss in the anterior corticospinal tract (A CST), lateral corticospinal tract (L CST), dorsal column (D Col) or with the mean axon loss across all assessed tracts. F+ SPMS = lymphoid‐like structure positive secondary progressive multiple sclerosis; F− SPMS = lymphoid‐like structure negative secondary progressive multiple sclerosis. Spearman r and P values reported. Significant correlations highlighted.