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A. Transversal ON and retina sections stained to detect demyelination (LFB), axonal loss (SMI312) and microglia/macrophages infiltration (Iba1) in H and EAE rats at 21 dpi. Quantification of demyelination (B), axonal loss (C) and Iba1+ cells (D) in H (n = 6) and EAE (n = 10) ONs at 21 dpi (*: P < 0.05). Data are expressed as mean ± SEM.
