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SAFB1 expression correlates with decreased Purkinje cell area in SCA patients. There was no significant correlation between SAFB1 staining in the nucleus and Purkinje cell area (A). However, increased cytoplasmic SAFB1 staining was correlated significantly with a decrease in Purkinje cell perikaryon area (B). Statistical analyses were carried out using Pearson correlation tests and the P and r values are depicted within each graph.
