Table 3.
Variables | Non‐edematous IIM* | Edematous myositis | P‐value** |
---|---|---|---|
Age at diagnosis | 46 [33.2; 58.7] | 52 [45.2; 58.66] | 1 |
Women | 117 (67.2%) | 10 (58.8%) | 1 |
CK level (UI/L) | 5000 [1710; 10372.7] | 5118 [1654; 6928] | 1 |
Muscle weakness | 154 (88.5%) | 15 (88.2%) | 1 |
Dysphagia | 82 (47.4%) | 12 (70.6%) | 1 |
Cancer | 25 (14.4%) | 4 (25%) | 1 |
Raynaud | 46 (26.74%) | 2 (11.8%) | 1 |
Arthritis | 36 (21.6%) | 0 (0%) | 1 |
Capillary C5b‐9 deposition | 47 (37%) | 13 (92.9%) | 0.003 |
MCH class 1 expression | 106 (85.5%) | 14 (100%) | 1 |
DM skin rash | 52 (29.9 %) | 9 (52.9 %) | 1 |
Interstitial lung disease | 74 (44.6%) | 1 (5.9%) | 0.07 |
MSA | |||
DM‐specific | <0.00001 | ||
MDA5 | 7 (4%) | 0 (0%) | |
Mi‐2 | 12 (6.9%) | 1 (5.9%) | |
NXP2 | 3 (1.7%) | 2 (11.8%) | |
NXP2‐SAE | 0 (0%) | 1 (5.9%) | |
SAE | 2 (1.1%) | 1 (5.9%) | |
TIF1γ | 3 (1.7%) | 3 (17.6%) | |
IMNM‐specific | |||
HMGCR | 31 (17.8%) | 0 (0%) | |
SPR | 34 (19.5%) | 0 (0%) | |
ASyS | |||
Jo1 | 39 (22.4%) | 0 (0%) | |
PL‐12 | 3 (1.7%) | 0 (0%) | |
PL‐7 | 5 (2.9%) | 0 (0%) | |
Seronegative | 35 (20.1%) | 7 (41.2%) | |
Not done | 0 (0%) | 2 (11.8%) | <0.00001 |
Abbreviations: DM = dermatomyositis; IMNM = immune mediated necrotizing myositis; IIM = idiopathic inflammatory myositis; MSA = myositis specific antibodies; ASyS = antisynthetase syndrome.
n (%) or median [Q1; Q3].
Adjusted P‐value Benjamini Hochberg.