Figure 1.

Coadministration of glucocorticoids (GCs) with ICIs can be classified into three phases: prophylaxis coinciding with day 1 for patients treated in combination with HEC drugs such as carboplatin, secondary immune modulation coinciding with irAEs or baseline chronic treatment in patients with chronic autoimmune disease or organ transplants. irAEs are associated with an active therapeutic response, with unmasking of preexisting anti‐tumoral immunity by ICIs. Approximate doses are shown as prednisolone equivalents in milligrams, with 12 mg dexamethasone approximately equivalent to 80 mg prednisolone.Abbreviations: HEC, highly emetogenic chemotherapy; ICI, immune checkpoint inhibitor; irAE, immune‐related adverse effect.