Table 1.
Baseline characteristics of study participants.
| Characteristics | Total (n = 346) | iPTH < 150 pg/mL (n = 110) | 150≤iPTH≤300 pg/mL (n = 94) | iPTH > 300 pg/mL (n = 142) | p-Value |
|---|---|---|---|---|---|
| Age, (years) | 62.08 ± 14.56 | 66.02 ± 9.99 | 61.68 ± 13.93 | 59.25 ± 14.71 | <0.001 |
| Male sex, n (%) | 182 (52.60) | 56 (50.91) | 58 (61.70) | 68 (47.89) | 0.105 |
| Smoking, n (%) | 106 (30.64) | 29 (26.36) | 32 (34.04) | 45 (31.69) | 0.465 |
| BMI (kg/m2) | 22.67 ± 3.42 | 22.28 ± 3.63 | 22.09 ± 3.44 | 23.34 ± 3.13 | 0.008 |
| Diabetes mellitus, n (%) | 194 (56.07) | 86 (78.18) | 46 (48.94) | 62 (43.66) | <0.001 |
| Hypertension, n (%) | 294 (84.97) | 92 (83.64) | 74 (78.72) | 128 (90.14) | 0.050 |
| Medication use | |||||
| Phosphate binders, n (%) | 204 (58.96) | 52 (47.27) | 48 (51.06) | 104 (73.24) | <0.001 |
| Vitamin D, n (%) | 146 (42.20) | 50 (45.46) | 36 (38.30) | 60 (42.25) | 0.587 |
| Cinacalcet, n (%) | 37 (10.69) | 11 (10.00) | 10 (10.64) | 16 (11.27) | 0.949 |
| Vascular access type | |||||
| Arteriovenous fistula, n (%) | 170 (49.13) | 50 (45.46) | 51 (54.26) | 69 (48.59) | 0.450 |
| Catheter, n (%) | 174 (50.30) | 59 (53.64) | 42 (44.68) | 73 (51.41) | 0.418 |
| Other, n (%) | 2 (0.58) | 1 (0.91) | 1 (1.06) | 0 | 0.491 |
| Laboratory parameters | |||||
| Hemoglobin (g/L) | 110.92 ± 16.20 | 107.35 ± 15.91 | 111.43 ± 15.61 | 113.37 ± 16.42 | 0.013 |
| Albumin (g/L) | 37.82 ± 4.50 | 34.99 ± 4.14 | 38.09 ± 4.94 | 39.83 ± 3.14 | <0.001 |
| Triglycerides (mmol/L) | 2.08 ± 1.14 | 1.97 ± 0.89 | 1.87 ± 1.05 | 2.30 ± 1.31 | 0.009 |
| Total cholesterol (mmol/L) | 4.33 ± 1.04 | 4.55 ± 1.00 | 4.20 ± 1.25 | 4.25 ± 0.90 | 0.028 |
| hs-CRP (mg/L) | 7.93±5.53 | 10.18 ± 7.46 | 7.02 ± 4.45 | 6.79 ± 3.59 | <0.001 |
| Calcium (mmol/L) | 2.23 ± 0.20 | 2.25 ± 0.17 | 2.22 ± 0.20 | 2.23 ± 0.21 | 0.405 |
| Phosphorus (mmol/L ) | 1.98 ± 0.63 | 1.54 ± 0.35 | 1.84 ± 0.61 | 2.40 ± 0.55 | <0.001 |
| iPTH (pg/ mL) | 259 (118.448) | 81 (51.116) | 220 (173.280) | 541 (393.646) | <0.001 |
| 25 (OH)VitD (mg/mL) | 9.25 ± 3.71 | 9.66 ± 3.45 | 8.60 ± 3.39 | 9.37 ± 4.07 | 0.114 |
| eGFR (ml/min/1.73 m2) | 6.724 ± 0.587 | 6.646 ± 0.611 | 6.756 ± 0.509 | 6.724 ± 0.587 | 0.321 |
| sp Kt/V | 1.39 ± 0.25 | 1.34 ± 0.21 | 1.40 ± 0.24 | 1.42 ± 0.27 | 0.036 |
Data were presented as mean ± SD or median (interquartile range) for continuous variables, and number (%) for categorical variables. BMI: body mass index; hs-CRP: high sensitive C-reactive protein; iPTH: intact parathyroid hormone; 25 (OH)VitD: 25-hydroxy vitamin D.