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. 2021 Mar 29;15:1357–1368. doi: 10.2147/DDDT.S282913

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© 2021 Hadisaputri et al.

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Protein expressions of the caspase-9, caspase-3, PARP-1, BCL-2 obtained by Western blotting in A549 cells treated with CA extract. (A) CA extract induced apoptotic cell death through activation of caspase-9 then triggered caspase-3. Moreover, BCL-2 antiapoptotic protein in A549 cells was suppressed after being treated with CA extract, shown in band and (B) bar graph. Quantitative data of band density measured using Image Studio Digits v. 5.2 (LI-COR Biosciences). One-way ANOVA followed with Tukey’s post hoc test was performed. *P <0.05.