Table 1.

Parameters of decision-Markov models

	Base value	Range	Distribution	Reference
Chort size	202349	-	-	24
Life span	82	-	-	25
Vaccination rate (first dose)	0.9995	0.9990–1.00	Triangular	Estimated
Rate of vaccine efficacy(Hep3)	0.977	0.932–0.995	Triangular	26
Transition probablity
HBsAg positive rate among mothers Perinatal infection rate of HBsAg mothers	0.031	0.01–0.0386		5,22,27
Universal vaccination	0.059	0.037–0.0926	Triangular	28–30
Nonvaccination	0.4034	0.3228–0.484	Triangular	31
Incidence of AHB ≥1 year	0.03	±50%	Triangular	32
AHB to carriers
<1	0.89	-	-	33
≥1	e^(−0.65*age^0.46)	-	-
Symptomatic		-	-	34
Age<1	0.01	-	-
1≤ age<10	0.1	-	-
Age≥ 11	0.3	-	-
AHB to CHB		-	-
Age≤5	0.25	-	-	35
6≤ age<19	0.06	-	-	36
Age≥20	0.04	-	-	36
Mortality of AHB	0.0041	0.003–0.015	Triangular	22,32
HBV Carriers to immunity		-	-
Age<20	0.012	-	-	34,37
Age≥20	0.0226	-	-	38
HBV Carriers to CHB	0.0269	-	-	39
HBV Carriers to Cirrhosis	0.001	-	-	19
HBV Carriers to HCC	0.002	0.0005–0.0061	Triangular	36
CHB to immunity	0.0005	-	-	32
CHB to cirrhosis	0.02	0.0081–0.027	Triangular	32,34,36
CHB to HCC	0.005	0.003–0.0064	Triangular	34,36
Mortality of CHB	0.014	0.0077–0.0158	Triangular	32,40
Cirrhosis to HCC	0.0465	0.028–0.066	Triangular	22,36
Mortality of cirrhosis	0.0663	0.0243–0.3932	Triangular	32,40
Mortality of HCC	0.5	0.081–0.545	Triangular	22,32,41
Mortality of other causes	Sample Survey Data of 1% of Population in 2015 in Beijing			42
Cost of vaccination (CNY/per dose)	36.86	±25%	Triangular	43
Cost of direct medical treatment(CNY)				Estimated
AHB	16,316.06	±25%	Triangular
CHB	14,743.24	±25%	Triangular
Cirrhosis	32,304.96	±25%	Triangular
HCC	112,324.15	±25%	Triangular
HBV carrier	761.95	±25%	Triangular
Discount rate	0.03	0.00–0.05	Triangular	44
Utility				32
Acute hepatitis B	0.892	±0.142	β
Chronic hepatitis B	0.912	±0.136	β
Cirrhosis	0.755	±0.209	β
Hepatocellular carcinoma	0.712	±0.254	β
HBV Carrier	0.968	±0.081	β

note: 1CNY = 0.15377US dollar in 2016⁴⁵