Figure 1.
Antimicrobial activities of II-6s against S. mutans. (a) Chemical structure of the small molecule compound II-6s. (b) Time-kill curve of II-6s or CHX against S. mutans at MBC. (c) Dose-dependent killing curve of II-6s or CHX against S. mutans within 5 min. Results are expressed as log10 (CFU/ml) and data are presented as means ± SD. (d) Scanning electron micrographs of S. mutans morphology after treatment with II-6s or CHX at MIC for 12 h. Negative control was untreated S. mutans. Yellow arrows indicate that the smooth surface of S. mutans cells became uneven and plicated