Figure 3.

The anti-demineralization effect of II-6s against three-species biofilms. (a) Representative transverse microradiography images of bovine enamel slabs exposed to three-species biofilm-induced experimental demineralization. The high-density regions represent the sound enamel tissues, while the low-density shadows indicate the caries-like lesions. (b) Lesion depth and (c) mineral loss of enamel slabs were calculated. Data are presented as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 as compared to the PBS treated control. N.S., not significant