Figure 4.

miR-129 modulates RB cell proliferation and apoptosis via MDM2/4 Y79 and WERI-RB-1 cells were co-transfected with miR-129 mimics and MDM2/4 overexpressing vector, cell viability was examined by MTT assay (a–b); DNA synthesis capacity was examined by FACS analysis (c–f); apoptosis of co-transfected RB cells examined by Flow cytometer assay (g–h). The data are presented as mean ± SD of three independent experiments. *P< 0.05, **P< 0.01, compared to control group; #P< 0.05, ##P< 0.01, compared to miR-129 mimics + NC group