Table 2.
Men | Women | |||||
---|---|---|---|---|---|---|
Variable | Area under the curve | Youden’s Index | Optimal cutpoint from Youden | Area under the curve | Youden’s Index | Optimal cutpoint from Youden |
Age, yrs | 0.68 | 0.13 | 78.90 | 0.61 | 0.33 | 79.00 |
Body mass index (BMI), kg/m2 | 0.68 | 0.10 | 30.06 | 0.64 | 0.30 | 27.55 |
Total body fat (TBF), kg | 0.68 | 0.09 | 23.72 | 0.64 | 0.32 | 30.21 |
Appendicular fat mass (AFM), kg | 0.69 | 0.10 | 9.53 | 0.64 | 0.33 | 15.93 |
Arm lean mass (ARMLM), kg | 0.69 | 0.10 | 5.80 | 0.63 | 0.32 | 4.71 |
Appendicular lean mass (ALM) | ||||||
ALM, kg | 0.70 | 0.10 | 22.36 | 0.62 | 0.31 | 18.01 |
ALM/Height, kg/m | 0.69 | 0.10 | 13.04 | 0.63 | 0.32 | 11.55 |
ALM/BMI, kg/kg/m2 | 0.73 | 0.10 | 0.84 | 0.62 | 0.30 | 0.56 |
ALM/TBF, kg/kg | 0.68 | 0.10 | 1.02 | 0.61 | 0.30 | 0.55 |
ALM/Weight, kg/kg | 0.69 | 0.11 | 0.28 | 0.61 | 0.30 | 0.24 |
ALM/Height2, kg/m2 | 0.68 | 0.10 | 7.44 | 0.63 | 0.31 | 7.14 |
ALM/Body Surface Area, kg/m2 | 0.69 | 0.10 | 11.64 | 0.61 | 0.30 | 10.45 |
ALM/Percent Fat, kg/% | 0.71 | 0.11 | 0.80 | 0.61 | 0.29 | 0.50 |
ALM/AFM, kg/kg | 0.69 | 0.10 | 2.75 | 0.61 | 0.30 | 1.27 |
Leg lean mass (LLM) | ||||||
LLM, kg | 0.70 | 0.10 | 16.09 | 0.62 | 0.31 | 13.27 |
LLM/Weight, kg/kg | 0.69 | 0.10 | 0.21 | 0.62 | 0.29 | 0.18 |
LLM/Height, kg/m | 0.69 | 0.09 | 9.71 | 0.62 | 0.30 | 8.22 |
LLM/ Height2, kg/m2 | 0.68 | 0.10 | 5.52 | 0.63 | 0.32 | 5.53 |
LLM/BMI, kg/kg/m2 | 0.73 | 0.10 | 0.62 | 0.62 | 0.31 | 0.41 |
LLM/TBF, kg/kg | 0.69 | 0.10 | 0.72 | 0.61 | 0.30 | 0.43 |
LLM/Body Surface Area, kg/m2 | 0.70 | 0.10 | 8.66 | 0.61 | 0.29 | 7.98 |
Maximum grip strength (GR) | ||||||
GR, kg | 0.76 | 0.12 | 34.00 | 0.63 | 0.32 | 19.00 |
GS/ALM, kg/kg | 0.73 | 0.10 | 1.60 | 0.65 | 0.29 | 1.36 |
GR/weight, kg/kg | 0.74 | 0.11 | 0.45 | 0.66 | 0.30 | 0.34 |
GR/BMI, kg/kg/m2 | 0.76 | 0.11 | 1.33 | 0.67 | 0.31 | 0.78 |
GR/Height, kg/m | 0.75 | 0.08 | 22.00 | 0.63 | 0.30 | 13.13 |
GR/Height2, kg/m2 | 0.74 | 0.10 | 12.13 | 0.63 | 0.31 | 8.25 |
GR/TBF, kg/kg | 0.71 | 0.11 | 1.66 | 0.64 | 0.31 | 0.82 |
GR/Body Surface Area, kg/m2 | 0.75 | 0.11 | 18.70 | 0.65 | 0.30 | 12.82 |
GR/LLM, kg/kg | 0.72 | 0.10 | 2.17 | 0.64 | 0.29 | 1.81 |
GR/Percent fat, kg/% | 0.75 | 0.11 | 1.31 | 0.64 | 0.30 | 0.57 |
GR/AFM, kg/kg | 0.72 | 0.12 | 3.98 | 0.64 | 0.33 | 1.44 |
GR/ARMLM, kg/kg | 0.73 | 0.09 | 6.08 | 0.65 | 0.30 | 5.37 |
Full abbreviations are defined in supplemental table S3. Variable units are presented without cancellation for clarity. The Youden index is a global test accuracy performance— it ranges from 0 (poor diagnostic accuracy) to 1.0 (perfect accuracy) 24. The optimal cut-point represents the value that optimizes both sensitivity and specificity. Note: Youden’s index for body weight and height were not calculated due to their overlap with body mass index.