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. 2021 Mar 31;28(1):655–669. doi: 10.1080/10717544.2021.1905748

Figure 2.

Figure 2.

Formation mechanism of LbL assembled NDDS. (a) Schematic illustrations of the LbL assembly of PAH/PSS multilayers coated PLGA nanoparticles via electrostatic interactions. (b) Transmission electron microscopic (TEM) image of the assembled PAH/PSS multilayers coated PLGA nanoparticles, scale bar: 50 nm. (c) Schematics of hydrogen bonding LbL assembly of block copolymer micelles. (d) Chemical structures of PCzEMA and PDNBMA for charge transfer interaction based LbL assembly. (e) UV-vis absorption spectra of assembled PCzEMA/PDNBMA nanocompositions. (f) Chemical structures of PPV and CdSe for covalent bonding based LbL assembly. (g) UV-vis absorption spectra of the assembled PPV–CdSe nanocompositions. Inset shows the dependence of optical absorbance at 470 nm on the number of layers. (a, b) Reproduced with permission (Luo et al., 2012). Copyright 2012, Wiley-VCH. (c) Reproduced with permission (Kim et al., 2008). Copyright 2018, American Chemical Society. (d, e) Reproduced with permission (Shimazaki et al., 1998). Copyright 2008, American Chemical Society. (f, g) Reproduced with permission (Liang et al., 2006). Copyright 2018, Wiley-VCH.