Table 1.
Medication | Target | Indication |
---|---|---|
Secukinumab (Novartis) | IL-17A | Plaque psoriasis Psoriatic arthritis Ankvlosing spondylitis |
lxekizumab (Lilly) | IL-17A | Plaque psoriasis Psoriatic arthritis Psoriatic arthritis |
Brodalumab (AstraZeneca) | IL-17RA | Plaque psoriasis |
Ustekinumab (Janssen) | IL-12 and IL-23 | Plaque psoriasis Psoriatic arthritis |
Guselkumab (Janssen) | IL-23 | Plaque psoriasis Psoriatic arthritis |
Risankizumab (AbbVie) | IL-23 | Plaque psoriasis |
Tildrakizumab (Sun Pharmaceuticals) | IL-23 | Plaque psoriasis |
Tofacitinib (Novartis) | JAK.l, JAK3 and a lesser degree JAK2 | Psoriatic arthritis Rheumatoid arthritis |
Baricitinib (Eli Lilly) | JAK1 and JAK2 | Rheumatoid arthritis |
Upadacitinib (AbbVie) | JAK1 | Rheumatoid arthritis |