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. 2021 Mar 19;11:603660. doi: 10.3389/fonc.2021.603660

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Copyright © 2021 Guo, Yan, Song, Wang, Wang, Liu, Huang, Li and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Landscapes of frequently mutated genes in esophageal cancer. (A) Oncoplot displaying the landscapes of frequently mutated genes in ESCA from the TCGA database. Genes are ordered according to their mutation frequency (left panel), and different mutation types were presented as indicated by the annotation bar (bottom). (B) Waterfall plot displaying the landscapes of frequently mutated genes in ESCA from the ICGC database. Genes are ordered according to their mutation frequency (left panel), and different mutation types were presented as indicated by the annotation bar (right panel). (C) Venn diagram displaying the common frequently mutated genes that were both of the top 30 high-frequency mutated genes in the TCAG database and ICGC database.