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. 2021 Apr 2;16(4):e0248900. doi: 10.1371/journal.pone.0248900

Table 4. Total Lung Capacity (TLC) values for participants by Indigenous status and stratified by sex and age (≤ 35 & > 35 years).

Indigenous Australian (n = 129) Australian Caucasians (n = 197) p-value
Total sample
TLC (L) 4.06 (3.87, 4.25) 5.09 (4.93, 5.24) <0.01*
TLC (%) 73.31 (70.62, 76) 89.94 (88.2, 91.69) <0.01*
TLC LLN 4.51 (4.35, 4.67) 4.62 (4.48, 4.76) 0.35
TLC < LLN 85 (66%) 41 (21%) <0.01*
Females
≤ 35 years n = 14 (18%) n = 11 (9%)
TLC (L) 4.09 (3.55, 4.63) 4.81 (4.31, 5.31) 0.048*
TLC (%) 81.21 (72.5, 89.92) 90.09 (83.32, 96.87) 0.11
TLC LLN 4.04 (3.76, 4.31) 4.33 (4.08, 4.58) 0.11
TLC < LLN 6 (43%) 2 (18%) 0.19
> 35 years n = 66 (82%) n = 124 (91%)
TLC (L) 3.59 (3.38, 3.81) 4.57 (4.44, 4.7) <0.01*
TLC (%) 73.14 (69.18, 77.1) 91.13 (88.79, 93.46) <0.01*
TLC LLN 3.95 (3.8, 4.09) 4.01 (3.94, 4.09) 0.36
TLC < LLN 43 (65%) 18 (15%) <0.01*
Males
≤ 35 years n = 14 (29%) n = 11 (18%)
TLC (L) 4.97 (4.37, 5.57) 6.44 (5.78, 7.1) <0.01*
TLC (%) 71.36 (63.43, 79.28) 91.45 (84, 98.91) <0.01*
TLC LLN 5.78 (5.48, 6.07) 5.88 (5.53, 6.23) 0.62
TLC < LLN 11 (79%) 2 (18%) <0.01*
> 35 years n = 35 (71%) n = 51 (82%)
TLC (L) 4.57 (4.21, 4.93) 6.11 (5.82, 6.4) <0.01*
TLC (%) 71.26 (66.28, 76.23) 86.71 (83.63, 89.78) <0.01*
TLC LLN 5.27 (5.06, 5.48) 5.87 (5.66, 6.08) <0.01*
TLC < LLN 25 (71%) 19 (37%) <0.01*

Abbreviations: TLC, Total lung capacity; LLN, Lower limit of normal.

Data were expressed as mean (95% confidence interval) and number (%).

TLC (%, LLN) data were derived from the NHANES (National Health and Nutrition Examination Survey) norms.

Differences between groups tested with two-tailed students T-test for continuous parameters and proportions z-test for categorical parameters.

*Denote statistically significant differences (p<0.05).