Table 3.
Multiple Regression of Physical Activity Levels and Overall AET Symptoms and Symptom Domains in Breast Cancer
| Symptom Domain | ||||||
|---|---|---|---|---|---|---|
| N | Overall ES | Vasomotor | Neurological | Gastrointestinal | Gynecological | |
| Parameter Estimate (Standard Deviation) | ||||||
| VIGOROUS ACTIVITY | ||||||
| None | 329 | REF | REF | REF | REF | REF |
| <60 min/week | 101 | −1.56(1.73) | −0.25(0.58) | −0.16(0.45) | −0.37(0.52) | −0.43(0.62) |
| ≥60 min/week | 55 | −2.61(1.33) | −0.35(0.45) | −0.33(0.35) | −0.41(0.40) | −1.16*(0.48) |
| P=0.13 | P=0.70 | P=0.63 | P=0.52 | P=0.05 | ||
| MODERATE ACTIVITY | ||||||
| None | 190 | REF | REF | REF | REF | REF |
| <60 min/week | 215 | −2.87(1.56) | −0.73(0.52) | −0.46(0.41) | −0.73(0.47) | −0.55(0.56) |
| ≥60 min/week | 80 | −3.43**(1.17) | −0.85*(0.39) | −0.59(0.31) | −0.57(0.35) | −1.13**(0.42) |
| P=0.02 | P=0.08 | P=0.43 | P=0.17 | P=0.03 | ||
| TOTAL PHYSICAL ACTIVITY | ||||||
| None | 231 | REF | REF | REF | REF | REF |
| <60 min/week | 135 | −1.99(1.35) | −0.68(0.45) | 0.13(0.35) | −0.42(0.40) | −0.65(0.48) |
| ≥60 min/week | 119 | −2.06(1.30) | −0.55(0.43) | 0.02(0.34) | −0.31(0.39) | −0.82(0.47) |
| P=0.18 | P=0.24 | P=0.93 | P=0.52 | P=0.16 | ||
Abbreviations: ACS=American Cancer Society; CI=confidence interval; ES=Endocrine Symptoms Scale
Test for linear regression parameter estimate=0
P<0.05
P<0.001
P<0.0001
Multivariable-adjusted regression model. Covariates: age (continuous), race (black, white), marital (married/living with partner, single/divorced/widowed), education (≤ high school, ≥ some college), income (<$60,000, $60,000 - <100,000, ≥$100,000, Unknown), body mass index (<25, 25 - <30, ≥30 kg/m2), cancer stage (0, I, II, III/IV, unknown), comorbidities (1, >1, unknown), Time since AET initiation (≤6months, >6 months, unknown), Time since diagnosis (≤1 year, >1 year, unknown), tangible support (score ≤15, 16–19, >19), emotional/informational support (score ≤31, 32–39, >39).