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. Author manuscript; available in PMC: 2021 Apr 2.
Published in final edited form as: Mol Genet Metab. 2017 Aug 20;122(1-2):18–32. doi: 10.1016/j.ymgme.2017.08.006

Table 4.

Guidelines for the treatment of Vitamin D deficiency from the Endocrine Society [43].

Infants and toddlers 0–1 year

  • 2000 IU/day (vitamin D2 or D3) for 6 weeks

  • Maintenance therapy of 400–1000 IU/day after the serum 25(OH)D level is above 30 ng/mL

  • Follow levels in 4 weeks
Children 1–18 years

  • 2000 IU/day (vitamin D2 or D3) for 6 weeks or 50,000 IU once weekly (vitamin D2) for at least 6 weeks

  • Maintenance therapy of 600–1000 IU/d after the serum 25(OH)D level is above 30 ng/mL
Adults

  • 50,000 IU once weekly (vitamin D2 or D3) for 8 weeks or 6000 IU/day (vitamin D2 or D3)

  • Maintenance therapy of 1500–2000 IU/d after the serum 25(OH)D level is above 30 ng/mL
Unique dosing needs for obesity, malabsorption, abnormal vitamin D metabolism (e.g. secondary to medications)

  • Minimum initial treatment with 6000–10,000 IU/day of vitamin D

  • Maintenance therapy of 3000–6000 IU/d after the serum 25(OH)D level is above 30 ng/mL