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. Author manuscript; available in PMC: 2021 Apr 2.
Published in final edited form as: Mol Genet Metab. 2017 Aug 20;122(1-2):18–32. doi: 10.1016/j.ymgme.2017.08.006

Table 6.

Challenges to skin integrity in the leukodystrophy population.

  • Limited mobility

  • Orthotic devices or adaptive hardware

  • Peripheral neuropathies

  • Urinary or fecal incontinence

  • Disease-specific predispositions to skin lesions (Aicardi-Goutières Syndrome and Sjogren-Larsson Syndrome)