Activity flow routes are better described by similar task conditions. A, Generalization of the task-state FC for each condition was tested across the whole-cortex task activation pattern for each condition, quantified by Pearson correlation r values. All cells of the matrix were significantly >0; p < 0.05 Bonferroni corrected for multiple comparisons. B, Identical to A, but with resting-state FC used instead of task-state FC. The number of time points going into each FC estimate was matched to the task-state FC estimates. Again, all cells of the matrix were significant; p < 0.05 Bonferroni corrected. Variation along the y-axis reflects the effect of the amount of time contributing to each FC estimate, while variation along the x-axis reflects the predictability of task activation patterns. C, Subtraction of the matrix in B from the matrix in A. D, Thresholded version of the matrix in C; p < 0.05 Bonferroni corrected. E, Similarity of task activation patterns across each pair of task conditions. Pearson correlations using whole-cortex activation patterns. F, Similarity of task-state FC patterns across each pair of task conditions. Pearson correlations across whole-cortex multiple-regression FC matrices.