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Characterization of αSyn oligomers. A, DLS characterization of αSyn monomer and oligomer preparations shows an increase in size distribution, indicating oligomer formation, shown as percentage of mass and apparent hydrodynamic diameter. B, Representative AFM analysis of αSyn monomer and oligomer preparations shows different αSyn strains/sizes in the oligomer preparation, including larger fibrils. Scale bars are located below each image.
