Skip to main content
. 2021 Mar 10;41(10):2264–2273. doi: 10.1523/JNEUROSCI.1871-20.2020

Figure 8.

Figure 8.

Schematic diagram showing dual oligomeric αSyn action on neurons and astrocytes. Right, αSyn directly activates eNMDAR-operated channels. Left, αSyn induces astrocytic glutamate release, which leads to further activation of eNMDARs. This aberrant eNMDAR activity in turn contributes to synaptic damage and loss. Created with www.BioRender.com.