Table 6.

Comparative analysis of reported in silico based identified phytochemicals and category A and B drugs on the basis of key molecular descriptors employed. The values represent mean values for the molecular descriptors.

Parametersa	Possible leads identified from in silico-based studies from natural sources against Covid-19	FDA-approved drugs for the antiviral/anti-infective category in the last 5 years (Category A)	FDA approved drugs derived from natural sources (Category B)
MW (g/mol)	456.33	513.97	603.95
TPSA (Å2)	147.92	145.50	195.61
nROTB	3.815	7.78	10.53
nHBDon	5.003	2.95	5.26
nHBAcc	9.085	9.13	12.38
AlogP	−1.30	−0.86	2.14

^aRepresents mean value.