Table 1.
The EC50 values of fitted binding curves of anti-IL-1R7 antibody to immobilized recombinant human or rhesus IL-1R7 protein (upper) or to HEK-293-FreeStyle cells transiently expressing full-length human- or mouse-IL-1R7 encoding DNAs (bottom) as shown in Figure 1
| Antibody | hIL-1R7/EC50 (ng/ml) | rhIL-1R7/EC50 (ng/ml) |
|---|---|---|
| MAB 300 | 18.4 | 19.7 |
| MAB 304 | 14.2 | 13.6 |
| Antibody | HEK293/hIL-1R7 EC50 (ng/ml) | HEK293/mIL-1R7 EC50 (ng/ml) |
|---|---|---|
| MAB 300 | 64.6 | n.a. |
| MAB 304 | 39.6 | n.a. |