Table 2.

The EC₅₀ values of fitted binding curves of the inhibition of anti-IL-1R7 to IL-18-mediated proinflammatory signaling and cytokine production in human HEK-Blue-IL-18 cells (upper) or A549 cells stably transfected with the human IL-1R7/9 genes (middle) or KG-1 cells (bottom) as presented in Figure 2, A–C

Antibody	EC50 (ng/ml)
MAB 300	2851
MAB 304	3750
MAB1181 reference mAB	8315

Antibody	EC50 (ng/ml)
MAB300	336
MAB 304	994
MAB1181 reference mAB	>10,000

Antibody	EC50 (ng/ml)
MAB300	40.3
MAB 304	804
MAB1181 reference mAB	3523

EC₅₀ values calculated from fitting curves in Figure 2A (upper), Figure 2B (middle), and Figure 2C (bottom).