Fig. 7.

a g:Profiler pathway enrichment analyses with the KEGG database. b CORUM protein complexes known for annotated protein complexes revealed enrichment for B-Ksr1-MEK-MAPK-14-3-3 complex and Ksr1 complex (Ksr1, Mek, 14-3-3, Mapk), EGF stimulated. These protein complexes are enriched for MAPK cascade and neurogenesis. c Protein-protein interaction network and functional enrichment for the KEGG pathway with priority leads were visualized in Cytoscape. It presented the enrichment results with nodes representing gene-sets and edges representing protein-protein associations. Accordingly, these proteins contribute to a mutual function; nevertheless, they are not necessarily physically binding to each other. d Western blot analysis of hippocampal lysates of and mToxin treated mice using p44/42 MAPK (Erk1/2) antibody and Hsc70 antibody. N=6, *p<0.05 t test