Table 2.

Multivariable regression: mixed models of ppFEV₁ (N=6,653)

	ppFEV1
	Model 1		Model 2
	β (95% CI)	p-value	β (95% CI)	p-value
Intercept (ppFEV1 in 2016)	90.35 (89.47, 91.24)	<0.001	90.36 (89.47, 91.24)	<0.001
Smoke exposure	−3.27 (−4.23, −2.30)	<0.001	−3.27 (−4.24, −2.31)	<0.001
Teza/iva	1.01 (0.63, 1.39)	<0.001	1.24 (0.80, 1.69)	<0.001
Teza/iva × smoke exposure	-	-	−0.84 (−1.65, −0.03)	0.041
Paternal education
Less than high school	−4.58 (−7.19, −1.98)	0.001	−4.58 (−7.19, −1.98)	0.001
High school	−4.02 (−5.21, −2.82)	<0.001	−4.02 (−5.21, −2.81)	<0.001
Some college	−1.66 (−2.93, −0.40)	0.010	−1.66 (−2.92, −0.40)	0.010
College degree	1.00 (reference)		1.00 (reference)
Health insurance
Private only	1.00 (reference)		1.00 (reference)
Public only	−0.46 (−0.86, −0.07)	0.021	−0.46 (−0.86, −0.07)	0.021
Both private and public	−0.08 (−0.48, 0.32)	0.700	−0.08 (−0.48, 0.32)	0.706
None/other	−0.07 (−1.82, 0.40)	0.209	−0.07 (−1.82, 0.40)	0.210
Female sex	−1.18 (−2.03, −0.33)	0.006	−1.18 (−2.03, −0.33)	0.006
Race/ethnicity
White	1.00 (reference)		1.00 (reference)
Other	−1.08 (−2.73, 0.57)	0.198	−1.08 (−2.73, 0.57)	0.198
Hispanic	−3.70 (−5.19, −2.21)	<0.001	−3.70 (−5.19, −2.21)	<0.001
Age in 2016 (centered)	−1.63 (−1.79, −1.46)	<0.001	−1.63 (−1.79, −1.46)	<0.001
P. aeruginosa	−0.59 (−0.81, −0.37)	<0.001	−0.59 (−0.81, −0.37)	<0.001
delF608 homozygous	−0.84 (−1.71, 0.03)	0.059	−0.84 (−1.71, 0.03)	0.059
Annual rate of change × age in 2016	−1.85 (−2.03, −1.67)	<0.001	−1.85 (−2.03, −1.67)	<0.001
	0.03 (−0.04, 0.10)	0.418	0.03 (−0.04, 0.10)	0.420
Annual rate of change, squared × age in 2016	0.29 (0.22, 0.37)	<0.001	0.29 (0.22, 0.37)	<0.001
	−0.07 (−0.10, −0.04)	<0.001	−0.07 (−0.10, −0.04)	<0.001