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. 2021 Mar 4;13(3):e13687. doi: 10.7759/cureus.13687

Table 2. Composite and simple outcomes – univariate analyses.

ACEI – angiotensin-converting enzyme inhibitors; ARB – angiotensin II receptor blockers; CI – confidence interval; NS – not significant; OR – odds ratio

  30-day mortality/ventilation 30-day mortality 30-day ventilation
Variables OR CI 95% p OR CI 95% p OR CI 95% p
Age 1.04 1.02-1.06 <0.001 1.08 1.05-1.12 <0.001 0.97 0.95-0.99 0.006
Sex (male) 1.06 1.02-1.06 NS 1.11 0.66-1.88 NS 1.14 0.59-2-21 NS
Medical History                  
   Arterial hypertension 1.48 0.85-2.60 NS 2.00 1.10-3.77 0.027 0.89 0.45-1.84 NS
   Chronic pulmonary disease 1.41 0.72-2.78 NS 0.73 0.34-1.48 NS 2.22 1.00-4.74 0.042
   Obesity 0.51 0.25-0.99 0.052 0.54 0.25-1.10 NS 0.66 0.24-1.56 NS
   Active cancer 2.69 1.15-6.85 0.027 3.15 1.36-7.57 0.008 1.16 0.37-3.07 NS
   Chronic kidney disease 0.91 0.48-1.73 NS 1.48 0.77-2.83 NS 0.26 0.06-0.76 0.031
   Diabetes mellitus 0.98 0.60-1.68 NS 1.05 0.60-1.84 NS 0.88 0.42-1.76 NS
   Chronic heart disease 1.00 0.59-1.69 NS 1.57 0.91-2.71 NS 0.41 0.18-0.88 0.028
   Immunosuppression 0.45 0.06-2.13 NS 0.30 0.02-1.80 NS 0.76 0.04-4.58 NS
   Dyslipidemia 0.55 0.33-0.91 0.021 0.60 0.35-1.02 0.061 0.85 0.43-1.63 NS
   Atrial fibrillation 1.11 0.57-2.19 NS 1.39 0.69-2.74 NS 0.59 0.19-1.48 NS
Chronic medication                  
   ACEI/ARB 0.82 0.49-1.36 NS 0.85 0.50-1.45 NS 0.84 0.43-1.63 NS
   Statin 0.92 0.55-1.52 NS 0.73 0.43-1.25 NS 1.00 0.51-1.92 NS
   Antiplatelet 1.21 0.68-2.14 NS 1.38 0.76-2.48 NS 0.58 0.24-1.26 NS
   Anticoagulants 0.86 0.42-1.72 NS 1.15 0.55-2.35 NS 0.36 0.08-1.07 NS
Symptoms for >7 days 0.73 0.40-1.32 NS 0.30 0.13-0.60 0.001 2.70 1.34-5.39 0.005
Drugs during hospitalization                  
   Hydroxychloroquine 0.71 0.43-1.17 NS 0.34 0.20-0.59 <0.001 3.36 1.67-7.13 0.001
   Lopinavir/ritonavir 0.60 0.31-1.14 NS 0.78 0.39-1-50 NS 0.72 0.28-1-64 NS