Table 2.

Algorithm’s run-time using different simulations

Case-Controls	Total patients	Cases	Controls	Iterations	Run-time
1:4	100	10	90	100	0,33 s
1:4	1000	100	900	100	0,35 s
1:4	10,000	1000	9000	100	0,87 s
1:4	100,000	10,000	90,000	100	6,25 s
1:4	1,000,000	100,000	900,000	100	1 min, 3 s
1:4	10,000	1000	9000	100	0,89 s
1:4	50,000	1000	49,000	100	1,1 s
1:4	100,000	1000	99,000	100	1,6 s
1:4	500,000	1000	499,000	100	6,3 s
1:4	1,000,000	1000	999,000	100	12,7 s
1:4	10,000,000	1000	9,999,000	100	2 min, 7 s