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. 2021 Feb 25;112(4):1339–1347. doi: 10.1111/cas.14849

FIGURE 5.

FIGURE 5

Peripheral T‐cell lymphoma, not otherwise specified (PTCL‐NOS) classification from multiple aspects. Two master transcriptional factors, GATA3 and TBX21, divide PTCL‐NOS into two groups with a different clinical course. Genetically, PTCL‐NOS is classified into three groups. T follicular helper (TFH)‐related genes represent TET2, RHOA, IDH2, and DNMT3A. Signatures of microenvironmental immune cells stratify PTCL‐NOS prognosis. From a clinicopathological aspect, PTCL‐NOS can be further divided, and the group may have characteristic genomic findings