Skip to main content
. 2020 Dec 2;7(2):159–167. doi: 10.1002/osp4.469

TABLE 3.

Prescription characteristics are shown for all weight‐negative medications, with each category further broken down into percentage (n) of total sample of prescriptions in each class as well as median (and range) of doses, duration of medication prescriptions, and interval follow‐up of MELD and weight in days

Weight‐loss medication % (n) Total dose median [range] Median time on treatment (days) [range] Median time to MELD follow‐Up (days) [range] Median time to weight follow‐Up (days) [range]
Metformin 63% (24) 1000 [500–2000] (mg/day) 1153 [172–2462] 363 [47–622] 335 [140–463]
GLP‐1 agonists 39% (15) 708 [36–1586] 353 [47–794] 296.5 [64–439]
Liraglutide 1.2 [1.2–2.4] (mg/day) 616.5 [36–1586] 353 [91–794] 305 [64–366]
Dulaglutide 0.75 [0.25–1.5] (mg/week) 567 [198–929] 327 [47–546] 140 [113–364]
Exenatide 15 [10–20] (mcg/day) a 875 [249–1166] 332.5 [228–441] 332 [228–439]
SGLT‐2 inhibitors 24% (9) 357 [12–1314] 363 [47–454] 326 [94–737]
Canagliflozin 300 [100–300] (mg/day) 357 [95–1314] 395 [94–454] 326 [94–737]
Dapagliflozin 5 (mg/day) 12 b c
Empagliflozin 10 [10–25] (mg/day) 519 [13–708] 47 252 [140–364]
Bupropion 16% (6) 225 [100–300] (mg/day) 926.5 [346–3509] 256 [244–349] 356.5 [258–618]
Topiramate 8% (3) 50 [25–75] (mg/day) 1011 [750–1011] 431 [391–589] 397 [376–500]
Phentermine 8% (3) 16 [15–30] (mg/day) 135 [29–146] 215 [213–217] 135 [29–151]
Naltrexone 5% (2) 27 [4–50] (mg/day) 734.5 [102–1367] 455 [101–809] 232.5 [101–364]
Lorcaserin 3% (1) 20 (mg/day) 275 317 330

Abbreviation: MELD, Model for End‐Stage Liver Disease.

a

A 2 mg/week dose was considered equivalent to 10 mcg/day.

b

No MELD labs meeting data collection criteria.

c

Excluded from weight loss analysis due to prescription period <30 days.