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Effect of cyclic stretch on vascular permeability. Representative images of red fluorescent dye (70 kDa RITC) leakage from the vasculature wall into the fibrin matrix. Vasculatures formed by HUVECs were exposed to CShigh for 24 h. Under static conditions, after 60 s, fluorescent dye leaks out of the vasculature. However, high magnitudes of cyclic stretch inhibit dye leakage from the vasculature wall.
