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. 2021 Mar 29;44(3):136–145. doi: 10.14348/molcells.2021.2239

Fig. 2. Accumulation of senescent cells in vivo.

Fig. 2

The composition of the senescent cell is different for each organ. Due to aging, heterogeneity between cells increases, and some cells become senescent. Although senescent cells are a rare population in tissue, SASP secreted by senescent cells not only affects neighboring cells but also travels through the blood to affect other tissues. The percentage of senescent cells is high in adipose tissue and low in the lung. SAT, subcutaneous adipose tissue.