Table 1.
List of commonly changed genes in senescent cells
| Ensembl ID | Gene symbol | Status | Description | GO: Cellular component | Cell type | No. of RNA-seq |
|---|---|---|---|---|---|---|
| ENSG00000033100 | CHPF2 | Up | Chondroitin polymerizing factor 2 | Membrane | Fibroblast, endothelial cells | 17 |
| ENSG00000083444 | PLOD1 | Up | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Membrane | Fibroblast, endothelial cells | 17 |
| ENSG00000084444 | FAM234B | Up | Family with sequence similarity 234 member B | Membrane | Fibroblast, endothelial cells | 17 |
| ENSG00000112697 | TMEM30A | Up | Transmembrane protein 30A | Membrane | Fibroblast, endothelial cells | 17 |
| ENSG00000186866 | POFUT2 | Up | Protein O-fucosyltransferase 2 | Endoplasmic reticulum membrane | Fibroblast, endothelial cells, melanocytes, keratinocytes, astrocytes | 20 |
| ENSG00000197077 | KIAA1671 | Up | Unknown protein coding | Unknown | Fibroblast, endothelial cells | 17 |
| ENSG00000143815 | LBR | Down | Lamin B receptor | Membrane | Fibroblast, endothelial cells | 17 |
Fibroblast cells: WI-38, IMR90, HCA-2, BJ, HFF, MRC-5. Endothelial cells: HUVEC, HAEC.