Table 2.

Multiple cell types bulk RNA-seq studies (in vitro, senescence-specific)

	Hernandez-Segura et al., (2017)	Casella et al., (2019)
Cell lines	6 different fibroblast strains (BJ, IMR90, HFF, MRC5, WI38, and HCA2), human neonatal foreskin epidermal melanocytes, keratinocytes, human fetal astrocytes	Human diploid fibroblast from fetal lung (WI-38, IMR-90), human aortic endothelial cells (HAECs), human umbilical vein endothelial cells (HUVECs)
Induction stimuli	RS, OIS, IRIS, oxidative stress	RS, IRIS, OIS, doxorubicin
Platform	Illumina Hiseq 2000	Illumina Hiseq 4000
No. of common DEGs	55	68
p16 in DEGs	No	No

RS, replicative senescence; OIS, oncogene-induced senescence; IRIS, ionic radiation-induced senescence.