Table 6.
Effect of SeY on serum immunoglobulin and cytokine concentrations in weaned pigs upon oxidative stress.
| Items | Treatments | P value | ||||||
|---|---|---|---|---|---|---|---|---|
| CON | SSY | DT | DSY | SEM | SeY | Diquat | SeY × diquat | |
| TNF-α (pg/mL) | 466.99a | 427.6b | 464.92 a | 370.63b | 15.51 | 0.03 | 0.30 | 0.33 |
| IL-1β (ng/L) | 42.8a | 23.12c | 45.73a | 34.35b | 2.43 | <0.01 | 0.03 | 0.18 |
| IL-6 (ng/mL) | 2.46ac | 1.74bc | 3.04a | 1.91bc | 0.21 | 0.02 | 0.33 | 0.59 |
| TP (gprot/L) | 26.31b | 32.09a | 24.68b | 30.38a | 1.01 | <0.01 | 0.79 | 0.31 |
| IgG (μg/mL) | 306.35c | 588.03a | 323.27c | 497.36b | 28.74 | <0.01 | 0.09 | 0.02 |
| IgA (μg/mL) | 93.08b | 166.94a | 114.28b | 159a | 7.90 | <0.01 | 0.37 | 0.06 |
Values are means ± SEM, (n = 8), nonchallenged pigs (CON, fed with basal diet), diquat-challenged pigs (DT, fed with basal diet), and SeY-treated pigs (fed with basal diet containing 250 mg/kg SeY) challenged by sterile saline (SSY) or diquat (DSY). a,b,cMean values within a row with unlike superscript letters were significantly different (P < 0.05). TP: total protein; IgG: immunoglobulin G; IgA: immunoglobulin A; TNF-α: tumor necrosis factor-α; IL-6: interleukin-6; IL-1β: interleukin-1β.