TABLE 3.

Quantitative evaluation of cleaved caspases-3 and 8 immunopositivity.

%	CTR	CDDP	Pt(IV)Ac-POA	CDDP REC	Pt(IV)Ac-POA REC
Casp-3	6.66 ± 0.47	11.22 ± 0.27	30.48 ± 0.27	41.27 ± 0.57	61.02 ± 0.20
Casp-8	1.19 ± 0.09	10.34 ± 0.22	11.59 ± 0.27	28.57 ± 0.40	33.33 ± 0.34
Caspase-3
Bonferroni’s Multiple Comparison Test	ρ value
CTR vs. 40 μM CDDP	***
CTR vs. 10 μM Pt(IV)Ac-POA	***
CTR vs. 40 μM CDDP REC	***
CTR vs. 10 μM Pt(IV)Ac-POA REC	***
40 μM CDDP vs. 10 μM Pt(IV)Ac-POA	***
40 μM CDDP vs. 40 μM CDDP REC	***
40 μM CDDP vs. 10 μM Pt(IV)Ac-POA REC	***
10 μM Pt(IV)Ac-POA vs. 40 μM CDDP REC	***
10 μM Pt(IV)Ac-POA vs. 10 μM Pt(IV)Ac-POA REC	***
40 μM CDDP REC vs. 10 μM Pt(IV)Ac-POA REC	***
Caspase-8
Bonferroni’s Multiple Comparison Test	ρ value
CTR vs. 40 μM CDDP	***
CTR vs. 10 μM Pt(IV)Ac-POA	***
CTR vs. 40 μM CDDP REC	***
CTR vs. 10 μM Pt(IV)Ac-POA REC	***
40 μM CDDP vs. 10 μM Pt(IV)Ac-POA	*
40 μM CDDP vs. 40 μM CDDP REC	***
40 μM CDDP vs. 10 μM Pt(IV)Ac-POA REC	***
10 μM Pt(IV)Ac-POA vs. 40 μM CDDP REC	***
10 μM Pt(IV)Ac-POA vs. 10 μM Pt(IV)Ac-POA REC	***
40 μM CDDP REC vs. 10 μM Pt(IV)Ac-POA REC	***

*ρ < 0.05; **ρ < 0.01; ***ρ < 0.001.