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. 2021 Mar 22;8:633631. doi: 10.3389/fcvm.2021.633631

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Copyright © 2021 Yang, Zhao, Zhang, Wu, Sun, Kong and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screening and validating the most relevant genes for cardiomyocyte regeneration by combining GEO datasets. (A) Hub genes showing significant differences in three GEO datasets associated with cardiomyocyte regeneration and our study. (B) mRNA expression level of 16 hub genes in P0 and P7 rat heart tissues determined by the qPCR method. (C) mRNA expression level of eight genes in isolated and cultured cardiomyocytes as determined by the qPCR method. *P < 0.05, **P < 0.01, compared to the Day 0 group.