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. 2021 Jan 5;10:18–30. doi: 10.1016/j.ibneur.2020.11.003

Fig. 6.

Fig. 6

Spatiotemporal and kinetic gait deficits are less severe post-stroke in Tan IIA-NP treated pigs. A decrease in the average cadence of the pigs from pre-stroke to post-stroke was more severe in PBS control pigs opposed to Tan IIA-NP treated pigs (133.9 ± 2.71–64.8 ± 5.86steps/min vs. 135.7 ± 7.08–109.98 ± 0.00steps/min, respectively; A). The cycle time of the left front limb increased more drastically in PBS control pigs as compared to Tan IIA-NP treated pigs (0.46 ± 0.02–0.94 ± 0.08 vs. 0.44 ± 0.02–0.55 ± 0.00 s, respectively; B). The left front step time increased post-stroke in PBS pigs more so than Tan IIA-NP pigs (0.24 ± 0.01–0.49 ± 0.07 vs. 0.22 ± 0.01–0.27 ± 0.00 s, respectively; C). The swing percent of cycle decreased more for the left front limb of PBS control pigs than Tan IIA-NP pigs (49.4 ± 0.26–33.3 ± 1.77 vs. 49.1 ± 1.90–43.2 ± 0.00%, respectively; D). The left front stride length of pigs treated with PBS displaying a greater reduction in stride length relative to Tan IIA-NP pigs (78.38 ± 2.37–63.19 ± 3.94 vs. 84.87 ± 1.78–77.44 ± 0.00 cm, respectively; E). A larger decrease in mean pressure of the left front limb was noted for PBS control pigs but not Tan IIA-NP treated pigs (2.93 ± 0.03–2.67 ± 0.03 vs. 2.87 ± 0.03–2.88 ± 0.00 AU, respectively; F).