Table 1.
Clinical and demographic characteristics (n = 15,563).
| Parameter | COPD (n = 6572) | IPF(n = 8991) |
|---|---|---|
| Age, mean ± SD | 60.4 ± 6.3 | 61.1 ± 8.3 |
| Male, % | 3320 (49.1) | 6349 (70.6) |
| Ethnicity | ||
| White | 5918 (90.0) | 7244 (80.6) |
| Black | 508 (7.7) | 579 (6.4) |
| Hispanic | 87 (1.3) | 830 (9.2) |
| Other | 59 (9.0) | 338 (3.8) |
| FVC%, mean ± SD | 53.1 ± 17.1 | 46.7 ± 16.5 |
| FEV1%, mean ± SD | 21.9 ± 11.1 | 50.4 ± 16.5 |
| Initial LAS, mean ± SD | 32.5 ± 8.5 | 45.9 ± 18.7 |
| BMI, kg/m2, mean ± SD | 24.7 ± 4.2 | 27.2 ± 3.9 |
| CO, L/Min, mean ± SD | 5.2 ± 1.4 | 5.4 ± 1.4 |
| PAWP, mean ± SD | 12.3 ± 5.1 | 9.6 ± 5.3 |
| PAWP ≤ 15 mmHg, n (%) | 5078 (77.3) | 7974 (88.7) |
| PAWP >15 mmHg, n (%) | 1494 (22.7) | 1017 (11.3) |
| PVR, mean ± SD | 2.9 ± 1.8 | 3.4 ± 3.3 |
| PVR < 3 WU, n (%) | 4224 (64.3) | 4997 (55.6) |
| PVR ≥ 3 WU, n (%) | 2348 (35.7) | 3994 (44.4) |
| mPAP, mmHg, mean ± SD | 25.7 ± 7.4 | 25.6 ± 9.7 |
| mPAP < 25 mmHg, n (%) | 3127 (47.6) | 4712 (52.4) |
| mPAP ≥ 25 mmHg, n (%) | 3446 (52.4) | 4279 (47.6) |
| Transplant outcomes | ||
| Died | 318 (4.8) | 793 (8.8) |
| Transplanted | 5028 (76.5) | 7215 (80.2) |
| Still waiting | 391 (5.9) | 223 (2.5) |
| Removed | 835 (12.7) | 760 (8.5) |
Note: values presented are either mean ± SD or frequency (percent), where appropriate.
FVC: forced vital capacity; FEV1: forced expiratory volume; LAS: lung allocation score; CO: cardiac output; PAWP: pulmonary artery wedge pressure; PVR: pulmonary vascular resistance; WU: Wood units; mPAP: mean pulmonary arterial pressure; COPD: chronic obstructive pulmonary disease; IPF: idiopathic pulmonary fibrosis.