Table 2.
Candidate clusters in SARS-CoV-2 DEG and interaction map along with their enriched lung cell types
| Cluster | Enriched cell markers |
|---|---|
| C-1 (190 genes) | proliferating natural killer/T cells, proliferating basal, proliferating macrophage, adventitial fibroblasts, alveolar epithelial type 1 |
| C-2 (91 genes) | proliferating epithelial, ciliated, proliferating macrophage, classical monocytes, alveolar epithelial type 1, adventitial fibroblasts |
| C-3 (81 genes) | adventitial fibroblasts, lipofibroblasts, bronchial vessel 2, classical monocytes, mast cells |
| C-4 (73 genes) | ciliated, capillary endothelial cells |
| C-5 (40 genes) | ionocytes, proximal ciliated |
| C-6 (34 genes) | bronchial vessel 1, lipofibroblasts, mesothelial |
| C-7 (20 genes) | dendritic cells, mast cells, classical monocytes |
| C-9 (18 genes) | alveolar epithelial type 1, fibroblasts, basal, myofibroblasts, smooth muscle cells |
| C-10 (17 genes) | lymphatic, peribronchial, arterial |
| C-11 (15 genes) | dendritic, mast cells |
| C-13 (14 genes) | classical monocytes |
| C-18 (10 genes) | proliferating epithelial, proliferating T cells |
| C-22 (8 genes) | ionocytes, macrophages, proliferating T cells |
| C-30 (6 genes) | proliferating T cells |
| C-31 (6 genes) | Arteries |
| C-34 (5 genes) | plasma cells |
| C-35 (5 genes) | plasma cells |