. 2021 Mar 30;26(1):32–40. doi: 10.15430/JCP.2021.26.1.32

Table 1.

List of significantly changed metabolites involved in the fatty acid β-oxidation pathway

Metabolites	Biochemical pathways	Metabolites	Fold control

			A/WT	AF/WT
Mucosa	Medium chain fatty acid	5-dodecenoate (12:1n7)	0.48^b	0.4^b
	Long chain fatty acid	Margarate (17:0)	0.35^b	0.39^b
		Eicosenoate (20:1)	0.25^b	0.29^b
		Erucate (22:1n9)	0.23^b	0.34^b
	Polyunsaturated fatty acid (n3 and n6)	Docosadienoate (22:2n6)	0.34^b	0.44^b
	Polyunsaturated fatty acid (n3 and n6)	Dihomo-linoleate (20:2n6)	0.31^b	0.32^b
Plasma	Polyunsaturated fatty acid (n3 and n6)	Dihomo-linolenate (20:3n3 or n6)	0.43^b	0.59^b
	Polyunsaturated fatty acid (n3 and n6)	Docosapentaenoate (n6 DPA; 22:5n6)	0.46^b	0.51^b
	Fatty acid metabolism (Acyl Carnitine)	Acetylcarnitine	1.57^a	1.83^a
	Fatty acid metabolism (Acyl Carnitine)	Decanoylcarnitine	1.44^a	2^a

			AF/WT	AF/A

Mucosa	Fatty acid metabolism (Acyl Carnitine)	3-hydroxybutyrylcarnitine	4.34^a	2.73^a
Mucosa	Fatty acid metabolism (Acyl Carnitine)	Stearoylcarnitine	1.68^a	1.4^a
Plasma	Fatty acid metabolism (Acyl Carnitine)	Cis-4-decenoyl carnitine	1.94^a	1.69^a
		Laurylcarnitine	1.48^a	1.42^a
		Myristoylcarnitine	1.65^a	1.71^a
		Palmitoylcarnitine	1.6^a	1.84^a
		Stearoylcarnitine	1.92^a	1.5^a
		Myristoleoylcarnitine	1.54^a	1.62^a
		Suberoylcarnitine	3.5^a	3.08^a
		Adipoylcarnitine	3.5^a	2.51^a
	Ketone bodies	3-hydroxybutyrate (BHBA)	5.46^a	3.53^a

Fold change is calculated as the ratio of the Apc^Min/+ (A) vs. WT, Apc^Min/+-Ffar2^-/- (AF) vs. WT, and Apc^Min/+-Ffar2^-/- vs. Apc^Min/+. Fold change that is labeled ^a or ^b presents significantly increased or significantly decreased, respectively. WT, wild-type. P < 0.05.