Skip to main content
. 2021 Feb 24;13:1759091421991769. doi: 10.1177/1759091421991769

Figure 7.

Figure 7.

DNMT mRNA Expression Is Reduced Post-Stroke. DNMT1 mRNA expression was significantly reduced in both the (A) contralateral (F2, 26 = 6.713, p = 0.0045) and (B) ipsilateral (F2, 30 = 10.02, p = 0.0005) hemispheres of the LPS exposed stroke animals, when compared to sham controls. Similarly, DNMT3a mRNA expression was significantly reduced in the (C) contralateral hemisphere of LPS stroke animals (F2, 26 = 4.388, p = 0.0228), and in the (D) ipsilateral hemisphere of both saline and LPS stroke animals (F2, 30 = 9.661, p = 0.0006). No significant changes in DNMT3b mRNA expression were observed (E, F). Data are expressed as mean ± SEM; one-way ANOVA with Dunnett’s post hoc test; brackets connect statistically significant groups; **p < 0.01, ***p < 0.001, and ****p < 0.0001.