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. 2019 Dec 16;45(2):264–272. doi: 10.1016/j.jgr.2019.12.002

Fig. 6.

Fig. 6

Effects of orally administered gintonin on donepezil brain delivery system. (A) Donepezil (10 mg/kg) was administered intravenously 60 min after oral treatment of gintonin (100 mg/kg). (C) Gintonin (40 mg/kg) was administered intravenously 60 min after oral treatment of donepezil (10 mg/kg). CSF (A and C) and plasma samples (B and D) were collected within 5 min. The analysis of donepezil was described in Materials and methods. Values depict the mean ± standard error of mean (S.E.M.) *p < 0.05, compared with donepezil alone (n = 8).