Fig. 2.

G-Rb1 ameliorated swelling and bone tissue degradation in MIA-induced arthritis. Thicknesses of rat legs were measured using a Vernier caliper (top panel). The femur and tibia bones of MIA-induced OA rats administered with G-Rb1 (3 and 10 μg/kg) or DIC were analyzed by X-ray radiography (bottom panel). Knee joint thickness of the experimental groups is shown in the right panel. Significant differences between each group and the OA group are marked *p < 0.05 and **p < 0.01. G-Rb1, ginsenoside Rb1; OA, osteoarthritis; MIA, monoiodoacetate.